2022 Toyota Sienna vs 2022 Honda Odyssey comparison

2022 Toyota Sienna vs. 2022 Honda Odyssey


Starting Price

2.5L Hybrid Engine


3.5L V6 Engine
36 City/36 Highway MPG

EPA-Estimated Fuel Economy

19 City/ 28 Highway
33.5 cubic feet

Cargo Room

32.8 cubic feet
Toyota Safety Sense™ 2.0 (TSS-2.0)

Safety System

Honda Sensing

All-Wheel Drive?


Are you shopping for a new minivan for your Kennesaw commute? The 2022 Toyota Sienna and the 2022 Honda Odyssey are top performers in their class, but which model is right for you? Overall, both vans have the performance, safety, and interior space your family wants, but the team at Marietta Toyota believes the better engine performance, AWD system, larger rear cargo area, and comprehensive safety system of the Toyota Sienna will fit your needs best. Compare these 2022 Toyota vs. Honda minivans with Marietta Toyota below, and then contact our team to arrange a time for a test drive.

2022 Sienna vs. Odyssey: Safety & AWD

When you shop for a new family van for your Atlanta commute, you want to make sure that it will keep you and your family safe whether you’re running an errand or taking a weekend road trip. When you compare the Toyota Sienna safety vs. Honda Odyssey safety, drivers will find that both models offer a comprehensive safety system that will keep their families protected. However, the Toyota Safety Sense™ 2.0 (TSS-2.0) system on the Toyota Sienna offers more features on its base trim level than the Honda Sensing suite on the Honda Odyssey. Compare the Toyota Sienna safety vs Odyssey safety features below:

2022 Toyota Sienna

  • Toyota Safety Sense™ 2.0 (TSS-2.0)
  • Blind Spot Monitor
  • Rear Cross-Traffic Alert
  • Hill Start Assist Control
  • Front and Rear Parking Assist with Automatic Breaking
  • Tire Pressure Monitoring System
  • Available All-Wheel Drive (AWD)

2022 Honda Odyssey

  • Honda Sensing
  • Collision Mitigation Braking System™
  • Road Departure Mitigation System
  • Multi-Angle Rearview Camera
  • Adaptive Cruise Control w/Low-Speed Follow

An additional safety feature offered by the Toyota Sienna is the available All-Wheel Drive (AWD) system. Whether you’re taking on inclement weather or going down the road less traveled, the Toyota Sienna model’s AWD system will help you navigate tricky terrain to ensure you and your passengers arrive safely to your destination. The Honda Odyssey does not offer AWD.

2022 Sienna vs. Odyssey: Fuel Economy

While both the Honda Odyssey and the Toyota Sienna have strong engine performance for your Smyrna commute, the Toyota Sienna offers a higher fuel economy rating than the Honda Odyssey. Redesigned in 2021 as a hybrid vehicle, the Toyota Sienna offers up to 36 City and 36 Highway EPA-Estimated fuel economy on its 2.5L hybrid engine. The Honda Odyssey, by comparison, can only offer 19 City/28 Highway EPA-Estimated fuel economy on its 3.6L V6 engine. While the Honda Odyssey can produce up to 280 horsepower for your commute, the Toyota Sienna model’s 245 net combined horsepower rating is more than enough for your trips around town and your weekend adventures. Save more on fuel and enjoy phenomenal performance when you take home a 2022 Toyota Sienna from Marietta Toyota!

Test Drive the Toyota Sienna at Marietta Toyota

Now that you’ve compared these 2022 Toyota vs. Honda minivans, visit our Marietta showroom to explore the 2022 Toyota Sienna and see why so many families prefer this hybrid van to the Honda Odyssey. Our friendly team will help you find the right Honda Odyssey model for your daily commute and we’ll even help you save with our new vehicle specials. Fill out our online finance application today to get behind the wheel of a new Toyota Sienna!

*MSRP excludes the Delivery, Processing, and Handling Fee of $995 for Cars (Yaris HB, Yaris, Yaris iA, 86, Corolla, Corolla HB, Camry, Camry HV, Prius LB, Prius c, Prius Prime, Mirai, Avalon, Avalon HV, Supra), $1,175 for Small/Medium Trucks, SUVs and Van (C-HR, RAV4, RAV4 HV, Highlander, Highlander HV, 4Runner, Sienna, Tacoma), $1,365 for Large SUVs (Sequoia, Land Cruiser), and $1,595 for Large Truck (Tundra). (Historically, vehicle manufacturers and distributors have charged a separate fee for processing, handling and delivering vehicles to dealerships. Toyota’s charge for these services is called the “Delivery, Processing and Handling Fee” and is based on the value of the processing, handling and delivery services Toyota provides as well as Toyota’s overall pricing structure. Toyota may make a profit on the Delivery, Processing and Handling Fee.) Excludes taxes, license, title and available or regionally required equipment. The Delivery, Processing and Handling Fee in AL, AR, FL, GA, LA, MS, NC, OK, SC and TX will be higher. The published prices do not apply to Puerto Rico and the U.S. Virgin Islands. Actual dealer price will vary.

Marietta Toyota 33.9339893, -84.5129133.